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Multiband mucosectomy safe and effective for treating Barrett's esophagus

April 22, 2016

All MBM procedures in the study were performed with the Duette? Multi-Band Mucosectomy kit from Cook Medical. The kit has a modified variceal band ligator as well as a hexagonal snare for performing resections. Because each ligator contains six rubber bands, the surgeon can perform up to six resections. The MBM study was conducted between November 2004 and October 2009 at Academic Medical Center in Amsterdam and the Sint Antonius Hospital in Nieuwegein, Netherlands. The data include 170 patient...

Millennium presents three studies in relapsed multiple myeloma at IMW meeting

April 21, 2016

Phase 1 Dose-Escalation Study of Investigational Agent MLN9708, An Oral Proteasome Inhibitor, in Patients with Relapsed or Refractory Multiple MyelomaThe interim data from this ongoing study were collected from 35 relapsed/refractory multiple myeloma patients, all of whom had received at least two prior therapies, which must have included VELCADE, lenalidomide or thalidomide, and corticosteroids. Of the 26 patients in the dose-escalation cohorts, 15 were refractory to VELCADE; of the 15 patients...

Scripps Research receives CIRM grant for new research in stem cell biology and disease origins

April 20, 2016

HIV prevalence was higher among those testing for HIV in the clinic-based testing areas than in the community-based areas. But due to the larger number of people tested in community-based areas, these programs detected almost four times as many HIV cases as the clinic-only programs across the three study sites (952 vs. 264). Repeat HIV testing in community-based program areas increased in all sites by the end of the three-year intervention period, reaching 28 percent of all those who were initia...

Study to examine how breastfeeding impacts cost of healthcare for very low birth weight babies

April 19, 2016

The grant will enable researchers at Rush to conduct a five-year study involving the largest prospective cohort of 600 very low birth weight infants born to racially and economically diverse mothers. The study will have a representative number of African American and low income women enrolled in this study. ???Unlike other institutions with the same demographics, the mothers that give birth at Rush elect to provide breast milk because they are encouraged to think of their milk as ???medicine' f...

Genome epigenetic analysis reveals new ways to detect and treat breast cancer

April 18, 2016

"I think we can harness epigenetic information to improve cancer care in several ways," Dr Dedeurwaerder said. "Firstly, several lines of evidence suggest that epigenetic dysregulation occurs early during carcinogenesis and can be detected in bodily fluids. Therefore, DNA methylation markers could help to provide an earlier detection of the disease.""Secondly, it has already been shown that DNA methylation markers might help to better stratify patients in terms of progno...